Statins

Cardiovascular Risk Score (QRISK2) and the Use of Statins 

As part of your regular health screening you may have recently had a cholesterol test. As you may know, the amount of cholesterol in your blood can increase your risk of developing Cardiovascular Disease (CVD). 

CVD can increase the risk of heart attacks, strokes, and other serious conditions. To work out your risk we use a tool called the QRISK2 calculator. 

Understanding QRISK2 

QRISK2 is a predictive algorithm used by medical practitioners to assess the potential risk of cardiovascular disease in patients. It calculates the likelihood of a patient having a stroke or heart attack in the next 10 years. The higher the score, the greater the risk. 

How QRISK2 Works 

QRISK2 takes into account various risk factors for CVD, including age, gender, ethnicity, high blood pressure, cholesterol level, body mass index (height and weight), smoking, alcohol intake, and certain medical conditions such as diabetes, rheumatoid arthritis, and chronic kidney disease. 

If you had a QRISK2 of 10-20%. This means that you have between a one to two in ten chance of having a stroke or heart attack in the next 10 years. 
 

What can I do to lower my risk? 

Guidance from NICE (National Institute for Health and Care Excellence) suggests that anyone with a score of more than 10% should be offered help to reduce their risk. This includes advice on making lifestyle changes and starting medication to lower cholesterol (statins). 

What lifestyle changes can I make? 

You may have noticed that the list of risk factors includes things we can change (such as smoking, weight and blood pressure) and things we cannot change (such as age and gender). We can therefore try to reduce our risk by taking a few simple steps including: 

  • Stop smoking. 
  • Eat a healthy balanced diet – low in fat, sugar and salt. Eat 5 fruit / veg a day. 
  • Reduce alcohol intake – aim for less than 14 units a week for men and women. 
  • Keep an eye on your weight and take steps to lose weight if needed. Aim for BMI 20-25. 
  • Exercise regularly (walking is a great start). 
  • Taking medication to reduce blood pressure if needed. 

The Role of Statins 

Statins are a class of prescription drugs that lower high cholesterol, especially LDL-cholesterol or “bad” cholesterol. They work by blocking a substance your body needs to make cholesterol and by helping your body reabsorb the cholesterol in your arteries. 

Benefits of Statins 

Statins can reduce the risk of cardiovascular disease by preventing plaque and blockages in the arteries. They can reduce your LDL cholesterol by around 30%, sometimes even 50% with high doses. Lowering cholesterol isn’t the only benefit associated with statins. These medications have also been linked to a lower risk of heart disease and stroke.